Efficacy of different schemes of supplementation with micronutrient powder for the control of anemia and micronutrient deficiency in children

Defining criteria to establish the optimum scheme of supplementation with micronutrient powder in children: unblinded randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN47136464

Enrollment

400

Registered

2013-05-23

Start date

2011-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia Nutritional, Metabolic, Endocrine

Interventions

There are 4 groups of supplementation: 1. Children from 6 to 11 months of age, who consume the micronutrient powder supplement intermittently for 6 months (90 doses), will have a significant decrease

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children between 6 months and 11 months and 29 days old 2. Residents in the city of Cajamarca and communities near the Health Center Baños del Inca 3. Born at term 4. Birth weight = 2500 g 5. Healthy 6. Hemoglobin> 8 g/dL (corrected for altitude) 7. Weight / length> -2 SD 8. Parents agree and sign the informed consent form

Exclusion criteria

Exclusion criteria: 1. Children younger than 6 months, or more than 12 months 2. Non-residents in Cajamarca (intervention site) 3. Children with initial hemoglobin below 8 g/dL (corrected for altitude) will be evaluated by the doctor to discard additional pathology and will be treated according to Ministry of Health standards 4. Weight/length below - 2 DE 5. Chronic, congenital or severe diseases 6. Parents do not sign the informed consent form

Design outcomes

Primary

Measure	Time frame
Anemia prevalence. All children are followed for 12 months, at entry and every month children are examined by a pediatrician at the outpatient clinic, every 2 weeks a field worker visits the child´s home to record compliance and morbidity, at entry and at the end of supplementation a venous blood sample of 5 ml is taken to measure hemoglobin, and micronutrients. In 2 more times we will take a drop of blood from the finger to measure hemoglobin.	—

Measure

Time frame

Anemia prevalence. All children are followed for 12 months, at entry and every month children are examined by a pediatrician at the outpatient clinic, every 2 weeks a field worker visits the child´s home to record compliance and morbidity, at entry and at the end of supplementation a venous blood sample of 5 ml is taken to measure hemoglobin, and micronutrients. In 2 more times we will take a drop of blood from the finger to measure hemoglobin.

—

Secondary

Measure	Time frame
1. Growth (weight and length) 2. diarrhea prevalence 3. micronutrient status (ferritin, transferrin receptors) 4. vitamin A 5. vitamin B12 6. zinc and folate status 7. inflamatory markers (CRP, AGP)	—

Countries

Peru

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026