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Exploring eye and phenotype characteristics in adults: high-definition oculo-phenomic evaluation study

High-Definition Oculo-Phenomic Evaluation (HOPE) Study: profiling the ocular and phenotypic traits in adults

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN47133398
Enrollment
2000
Registered
2024-02-29
Start date
2023-01-01
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adults with high myopia and non-high myopia control Eye Diseases

Interventions

The HOPE study is a retrospective and prospective ambispective cohort study that includes adults from Guangzhou, China. By conducting follow-ups every 2 years over a continuous period of 6 years, an a

Sponsors

Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adults 2. Permanent residents of Guangzhou (residing for more than 6 months) 3. Volunteers for this study and have signed an informed consent form

Exclusion criteria

Exclusion criteria: 1. Presence of severe ocular diseases, such as advanced cataract, glaucoma, retinal diseases, etc 2. History of corneal or intraocular surgery, radiotherapy, laser treatment 3. Presence of severe systemic diseases, such as coronary heart disease, myocardial infarction, stroke, multiple sclerosis, dementia, depression, mania, etc 4. History of life-threatening major disease treatments, such as cardiac stent placement, major surgery under general anesthesia, surgery for malignant tumors 5. Pregnant women, disabled individuals, those with communication barriers, or those unable to complete the examination

Design outcomes

Primary

MeasureTime frame
Retinal and choroidal structures and blood flow measured by optical coherence tomography angiography at baseline and each follow-up visit (2, 4 and 6 years)

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

China

Contacts

Public ContactWei Wang
wangwei@gzzoc.com+86 (0)20 87334687

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026