Covid-SMART: Optimising lateral flow testing for NHS staff release from quarantine and return from isolation

Covid-SMART release & return: urgent study of dynamic quarantine and isolation with alternative lateral flow devices and regimens

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN47058442

Enrollment

2000

Registered

2022-01-26

Start date

2022-01-31

Completion date

Unknown

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. Urgent study of dynamic quarantine and isolation with alternative lateral flow devices and regimens for NHS staff Infections and Infestations

Interventions

Urgent pilot service evaluation with randomised order of swabbing - nose/throat using Innova Lateral Flow Device (LFD) and nose only using Orient Gene LFD and internally controlled comparison of sing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: NHS staff working at Liverpool University Hospital Foundation Trust (LUHFT) sites who are fully vaccinated

Exclusion criteria

Exclusion criteria: LUHFT staff that are not fully vaccinated

Design outcomes

Primary

Measure	Time frame
Covid case detection measured by dual swabbing of two different manufacturers lateral flow devices at the same time daily for up to 10 days	—

Secondary

Measure	Time frame
The earliest day of detection of Omicron infection measured using nose only swabbing lateral flow device Orient Gene	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 5, 2026