Hypertension and cardiovascular risk Circulatory System Hypertension and cardiovascular risk
Conditions
Interventions
Current interventions as of 27/02/2020:
There are two study arms. Practices are randomly assigned on a 1:1 basis (using a computer algorithm) to either of two prescribing policies:
1. A policy of us
Sponsors
University of Dundee/NHS Tayside
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Registered patients with a documented diagnosis of hypertension and prescribed a thiazide, or thiazide-like, diuretic in a participating practice 2. Aged 18 years and older
Exclusion criteria
Exclusion criteria: Does not meet the inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The composite cardiovascular outcome (comprising non-fatal MI, non-fatal stroke, hospitalization for congestive heart failure, and vascular death) is measured using electronic record-linkage to national datasets of routinely collected data and supported by information from medical records. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Each individual component of the composite primary outcome will be included as a secondary outcome 2. All-cause mortality is measured using record-linkage to national datasets of routinely collected data The study is primary outcome driven so the outcomes are counted as they occur rather than at defined time periods. We expect that the follow-up process will take around 3 years to accrue sufficient events to power the study. | — |
Countries
Scotland, United Kingdom
Contacts
Public ContactAmy Rogers
Outcome results
None listed