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Preventive effects of Echinacea extract on cold and flu symptoms

Preventive effects of oral Echinacea purpurea dried herb extract against upper respiratory tract infections: a randomised double-blinded placebo-controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN46631134
Enrollment
120
Registered
2018-11-22
Start date
2001-10-01
Completion date
Unknown
Last updated
2021-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper respiratory tract infections (URTIs) Respiratory Upper respiratory tract infections (URTIs)

Interventions

Upper respiratory tract infection (URTI) scores will be taken during an 8 week pre-treatment period. After this, these secores are used to divide the subjects into lower and higher strata. From each o

Sponsors

University of Wolverhampton
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 2. Generally healthy

Exclusion criteria

Exclusion criteria: 1. Gastrointestinal ailments at the time of the study 2. Previous anaphylactic shock 3. Proneness to food allergies (specifically including sunflower seeds) 4. Severe eczema 5. Autoimmune disorders such as lupus or rheumatoid arthritis 6. Pregnant or breastfeeding

Design outcomes

Primary

MeasureTime frame
Upper respiratory tract infection incidence and severity, assessed at the baseline and weekly for the 8 week trial period using the severity scale of Grimm and Muller

Secondary

MeasureTime frame
1. The following baseline personal data, assessed by study investigators on a study-designed form following recruitment and prior to week 1 of the intervention dose period: 1.1. Gender 1.2. Age 1.3. BMI 2. The following lifestyle information, assessed using a self-report questionnaire at approximately week 4 of the intervention dose period: 2.1. Accomodation 2.2. Transport 2.3. Dietary supplements 2.4. Stress 2.5. Alcohol intake 2.6. Smoking 2.7. Exercise 3. Diet, assessed using a self-report diet diary form at week 4 of the intervention dose period 4. Subjective perceptions of benefit, side-effects and dose identification, assessed by questionnaire at week 8 of the intervention dose period

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026