The effect of nasal mupirocin, prior to percutaneous endoscopic gastrostomy (PEG), upon peristomal colonisation and infection

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN46568273

Enrollment

Registered

2004-09-30

Start date

2003-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-percutaneous endoscopic gastrostomy sepsis Injury, Occupational Diseases, Poisoning Complications of procedures

Interventions

Nasal mupirocin versus standard care (no prophylactic antibiotics). Mupirocin was administered for 5 days before PEG insertion. Nasopharyngeal swabs, PEG site appearance and bacteriology were record

Eligibility

Inclusion criteria

Inclusion criteria: Pilot study of 20 patients recruited, pilot study of 10 controls

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Pilot: Will access the practicalities of the study design, the consistency of the scoring tool and also give an indication of the bacteriology of nasal colonisation, peristomal colonisation and infection within the proposed research setting. Main: The primary outcome measure is that of perstomal infection.	—

Secondary

Measure	Time frame
Secondary outcomes of peristomal colonisation and risk factors for methicillin resistant staphylococcus aureus (MRSA) colonisation will also be measured.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026