'I can't forget to worry': cognitive behavioural therapy (CBT) for anxiety in people with dementia

A pilot randomised controlled trial of cognitive behavioural therapy (CBT) for anxiety in people with dementia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN46521766

Enrollment

Registered

2011-06-21

Start date

2011-06-01

Completion date

Unknown

Last updated

2018-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementias and Neurodegenerative Diseases Research Network

Interventions

1. Cognitve behaviour therapy (CBT) for people with anxiety and dementia 2. 25 will be randomised to the treatment group and 25 to the control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Meet DSMIV criteria for dementia in mild to moderate range 2. Clinical Dementia Rating score of 0.5, 1 or 2 3. Clinical anxiety, as determined by a score of 11 or above on the RAID (Rating Anxiety in Dementia) 4. Living in the community 5. The presence of a carer, who is willing to participate in the therapy 6. An ability to understand and communicate in English 7. Willing to engage in therapy involving discussion of thoughts and feelings 8. Male or female

Exclusion criteria

Exclusion criteria: 1. Co-morbid psychiatric disorder (e.g. psychosis) or challenging behaviour (e.g. severe agitation) likely to prevent engagement in therapy, not including anxiety or depression 2. Presence of a learning disability or severe physical illness, which could impact on participation, involving discussions of thoughts and feelings

Design outcomes

Primary

Measure	Time frame
Rating Anxiety in Dementia (RAID). This rates signs and symptoms of anxiety using interviews with carers and people with dementia. There are 18 questions in various categories: worry, apprehension, vigilance, motor tension and autonomic hypersensitivity. A score of 11 or above indicates significant clinical anxiety. It has good inter-rater and test-retest reliability, is sensitive to change and correlates with quality of life. Measured at baseline, 12 weeks and 6 months.	—

Measure

Time frame

Rating Anxiety in Dementia (RAID). This rates signs and symptoms of anxiety using interviews with carers and people with dementia. There are 18 questions in various categories: worry, apprehension, vigilance, motor tension and autonomic hypersensitivity. A score of 11 or above indicates significant clinical anxiety. It has good inter-rater and test-retest reliability, is sensitive to change and correlates with quality of life. Measured at baseline, 12 weeks and 6 months.

—

Secondary

Measure	Time frame
1. Cornell Scale for Depression in Dementia at 1, 12 and 24 weeks 2. Hospital Anxiety and Depression Scale (HADS) at 1, 12 and 24 weeks 3. Mini Mental State Examination (MMSE) at 1, 12 and 24 weeks 4. Quality of Caregiver and Patient Relationship (QCPR) at 1, 12 and 24 weeks 5. Quality of Life in Alzheimer's Disease (QOLAD) at 1, 12 and 24 weeks	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026