The Amsterdam Graded Activity Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN46141261

Enrollment

134

Registered

2007-05-30

Start date

1999-04-01

Completion date

Unknown

Last updated

2022-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low back pain Musculoskeletal Diseases Low back pain

Interventions

Graded activity: The graded activity intervention consisted of two sessions of physical exercises a week until full return to regular work was achieved. The intervention was supervised

Eligibility

Inclusion criteria

Inclusion criteria: 1. Sick leave because of non-specific low back pain. This could be either full or partial sick leave 2. A minimum duration of the complaints of four weeks in succession

Exclusion criteria

Exclusion criteria: 1. Radiation below the knee in combination with signs of nerve root compression 2. Cardiovascular contra-indications for physical activity, as checked by the Physical Activities Readiness Questionnaire 3. A conflict between worker and employer with legal involvement 4. Pregnancy

Design outcomes

Primary

Measure	Time frame
1. Days of sick leave due to low back pain 2. Disability 3. Pain	—

Secondary

Measure	Time frame
Pain-related fears	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026