Helicobacter pylori infection Infections and Infestations Bacterial infection of unspecified site
Conditions
Interventions
The urea-C13 breath test will be used to assess Helicobacter pylori (HP) infection. A questionnaire will be used to determine gastrointestinal symptoms and all volunteers who indicate having symptoms
Sponsors
University of Chile, Institute of Nutrition and Food Technology (INTA) (Chile)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Asymptomatic adults 2. Aged 35 - 45 years (women) and aged 25 - 45 years (men)
Exclusion criteria
Exclusion criteria: Gastrointestinal symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessed on days 17 and 38 of the study: 1. Fractional iron absorption, assessed by Eakins and Brown's double-isotope technique 2. Fractional zinc absorption, determined from the ratio of urinary enrichment of oral doses (67Zn and 70Zn) as a proportion of urinary enrichment of intravenous dose (68Zn) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Intragastric pH, assessed by the urine acid output test, assessed on days 1 and 24 of the study 2. Pepsinogen I and pepsinogen II will be determined by radioimmunoassay, assessed on day 3 of the study. Haemoglobin, serum iron, TIBC and transferrin saturation, serum ferritin and serum zinc, assessed on day 3 of the study 7. High sensitivity C-reactive protein, assessed on day 3 of the study | — |
Countries
Chile
Outcome results
None listed