Cardiovascular health Circulatory System
Conditions
Interventions
We conducted two consecutive types of intervention (diet alone vs diet plus exercise intervention) in a sequence over 12 months in a weight management program. The 12-month study period had a diet-alo
the diet-alone intervention was implemented by requesting all three groups not to do exercise for the first 3 months.
The study was a randomized intervention with three different exercise groups:
1.
assessors for all outcomes were blinded to participant group assignment, and all outcome data were kept blinded until the final data entry for the 12-month assessment was completed.
Sponsors
National Research Foundation of Korea (NRF) (South Korea)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy women aged between 18 and 65 years 2. Elevated waist circumference (greater than or equal to 85 cm) according to the criteria for abdominal obesity as defined by the Korean Society for the Study of Obesity (Lee et al. 2007) 3. Willing to be randomly assigned to one of three different exercise modes (i.e., aerobic, resistance and combination exercise training)
Exclusion criteria
Exclusion criteria: 1. Current medical conditions such as cardiovascular diseases, diabetes or cancers requiring physician supervision 2. Physical limitations restricting exercise ability 3. Use of hormone therapy 4. Participation in weight loss intervention during the last year 5. Weight change in the 4 weeks prior to participation in our study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endothelial dysfunction, as measured by flow-mediated dilation (FMD), at baseline, 3, 6 and 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Aortic stiffness, as measured by carotid-femoral pulse wave velocity 2. Carotid atherosclerosis, as measured by carotid intima-media thickness 3. Cardiometabolic factors 4. Psychosocial factors 5. Quality of life Measured at baseline, 3, 6 and 9 months | — |
Countries
Korea, South
Outcome results
None listed