Relationship between Overactivity, Stress and anxiety in Anorexia Nervosa

An investigation of the relationship between over activity (hyperactivity), anxiety, stress responsiveness and clinical outcomes in patients with anorexia nervosa (AN): a process outcome study in search for a phase advanced clinical marker

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN45581761

Enrollment

120

Registered

2011-08-04

Start date

2010-02-25

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, Eating disorders Mental and Behavioural Disorders Eating disorders

Interventions

Actiwatch: A non-invasive well-tolerated device that measures activity levels over a continuous 24-hour period. The device contains an accelerometer to measure the frequency of wrist movements every 1

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Diagnosis of anorexia nervosa (AN) or generalised anxiety disorder (GAD) 2. Females aged 18 years or older, up to 65 years 3. English speaking

Exclusion criteria

Exclusion criteria: 1. Male 2. Other psychiatric diagnoses 3. Presence of physical illness 4. Learning disability

Design outcomes

Primary

Measure	Time frame
BMI, measured weekly and at follow ups (after 6 months)	—

Secondary

Measure	Time frame
1. Actiwatch data, measured weekly for 8 weeks, at 12 weeks and 24 weeks 2. Body composition, measured at baseline, week 12 and 24 3. Questionnaire data, measured at baseline, week 12 and 24 4. Salivary cortisol, measured weekly for 8 weeks, and at follow ups	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026