Pilot randomised controlled trial of deep brain stimulation in Tourette syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN45455499

Enrollment

Registered

2007-07-06

Start date

2008-04-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tourette syndrome Mental and Behavioural Disorders Somatoform disorders

Interventions

Current interventions as of 05/12/2007: Group 1: Group 1 will have deep brain stimulation electrodes placed in the globus palludus internum. After 6 weeks, the electrodes will be switched on and adjus

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adults with medically intractable Tourette syndrome for whom surgery and post-operative care is not contraindicated.

Exclusion criteria

Exclusion criteria: 1. Tics for other neurological reasons 2. High risk for surgery or post-op care

Design outcomes

Primary

Measure	Time frame
Yale Global Tic severity scale.	—

Secondary

Measure	Time frame
1. Yale-Brown Obsessive Compulsive Scale 2. Hospital Anxiety and Depression Scale 3. Total Subjective Quality Of Life (TS-QOL)	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026