Kinetics of solute removal with on-line hemodiafiltration: influence of duration and frequency of treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN45403612

Enrollment

Registered

2006-02-02

Start date

2000-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease Nutritional, Metabolic, Endocrine Renal disease

Interventions

Modification of treatment mode, frequency, drawing and analysis of blood samples

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Stable patients with renal end stage disease being on hemodialysis for at least six months 2. Residual urine volume less than 200 ml per day 3. Ages betweeen 18 and 75 years 4. Body dry weight between 60 and 80 kg 5. Written consent 6. Well functioning vascular access

Exclusion criteria

Exclusion criteria: 1. Known human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV) infection 2. Miscellaneous acute or chronic infections 3. Known coagulation disturbances 4. Known incompliance with respect to fluid restriction

Design outcomes

Primary

Measure	Time frame
Blood concentrations of small and large molecular weight uremic solutes	—

Secondary

Measure	Time frame
Modelling of solute kinetics	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026