Cancer: Oesophageal Cancer Oesophageal
Conditions
Interventions
Thalidomide will be prescribed strictly in accordance with the regulations laid down by S.T.E.P.S. (System for Thalidomide Education & Prescribing Safety). Patients will be established on an isocalori
quality of life questionnaire (Karnofsky Index), nutritional status, and a detailed neurological examination will be conducted to look for evidence of neurotoxicity. Sensory nerve action potential amp
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Inclusion criteria
Inclusion criteria: 12 oesophageal cancer patients will be recruited from the endoscopy database. Inclusion criteria: 1. Patients with non obstructing and inoperable oesophageal cancer 2. Able to swallow a semi solid diet (Dysphagia score <3)
Exclusion criteria
Exclusion criteria: 1. Pre menopausal women 2. Patients receiving any adjuvant chemo or radiotherapy 3. Patients with oesophageal obstruction 4. Patients with established neuropathy 5. Patients requiring frequent laser ablation sessions 6. Patients unable to take a constant calorific intake 7. Increased debility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in metabolic rate, weight gain and improvement in quality of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed