Mild cognitive impairment Mental and Behavioural Disorders
Conditions
Interventions
The study will be conducted in the setting of the IPS Plenamente Comprehensive Mental Health using the diagnostic database of this institution. Participant selection will be rigorously carried out wit
Sponsors
Universidad de Manizales
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis of MCI according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria, with symptom onset within the last 2 years and diagnosed by the neuropsychology department at least 6 months prior to inclusion 2. Score on the Montreal Cognitive Assessment (MOCA) between =15.1 and =20.5 3. Preservation of complex instrumental activities of daily living with the possibility of using compensatory strategies according to a score of 8 on the Lawton and Brody scale 4. Preservation of basic activities of daily living with a Barthel Index score between 91 and 100, indicating "mild dependence" or "complete independence," sufficient for participation in the study 5. A minimum of 5 years of formal education 6. Mild anxiety symptoms according to the Beck Anxiety Inventory (BAI) score, between 8 and 15 7. Impairment in executive functions according to scores obtained in the study tests (Card Sorting from the BANFE-2: Standardized score =7, Alphabetical Ordering from the BANFE-2 (trial 2 and 3): Standardized score =7, Digit Retention from the WAIS-IV: Scaled scores =7, Arithmetic from the WAIS-IV: Scaled scores =7, Corsi Blocks: Scaled score =7, Stroop Test Form A and B from the BANFE-2: Standardized score =7, Working Memory Index from the WAIS-IV: Scores =85) 8. Sufficient visual and/or auditory acuity to perform neuropsychological tests
Exclusion criteria
Exclusion criteria: 1. Associated neurological disorders 2. Scores on the Yesavage Geriatric Depression Scale (GDS-15) that do not indicate moderate to severe depressive symptoms (scores <6) 3. Psychiatric comorbidity other than anxiety symptoms 4. History of addiction within the last 10 years 5. Receiving cognitive training during the last 6 months prior to starting participation in the study 6. Hospitalization in an Intermediate Care or Intensive Care Unit within the last year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Working memory measured using the Working Memory Index of the WAIS-IV (subtests of Arithmetic and Digit Span), the Corsi Blocks test, the Alphabetical Ordering (trials 2 and 3) from the BANFE-2, and the Spatial Addition test from the WMS-IV at baseline and post-intervention 2. Cognitive flexibility measured using the Card Sorting from the BANFE-2 at baseline and post-intervention 3. Inhibitory control measured using the Stroop (Forms A and B) from the BANFE-2 at baseline and post-intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of anxiety symptoms measured using the Beck Anxiety Inventory (BAI) at baseline and post-intervention | — |
Countries
Colombia
Contacts
Public ContactMaría Alexandra ;Daniel Alfredo Cardona Tangarife;Landinez Martínez
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Outcome results
None listed