Mikono Safi Study - Hand hygiene intervention to optimise helminthic infections control: a cluster-randomised controlled trial in NW Tanzania

Cluster-randomised controlled trial to evaluate the effectiveness of an intervention for improving handwashing behaviour on the prevalence of soil transmitted helminth infections among primary school children in NW Tanzania

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN45013173

Enrollment

3200

Registered

2017-06-21

Start date

2017-08-01

Completion date

Unknown

Last updated

2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. Soil transmitted helminth infections 2. Water, sanitation and hygiene (WASH) related behaviour Infections and Infestations 1. Soil transmitted helminth infections 2. Water, sanitation and hygiene (WASH) related behaviour

Interventions

Participanting schools are randomised within geographical strata (districts). There are three districts (Bukoba Urban District, Bukoba Rural District and Muleeba District). Randomisation to either the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Primary school students 2. Male and female 3. Attending classes 1 - 6 4. aged 6 - 12 years

Exclusion criteria

Exclusion criteria: 1. Student not giving assent 2. Parent or guardian refusing consent

Design outcomes

Primary

Measure	Time frame
Combined prevalence of ascariasis and trichuriasis in students’ stool samples is measured by microscopy using the formol-ether concentration method to identify helminth ova, at baseline and about 12 months after initial deworming.	—

Secondary

Measure	Time frame
1. Hand-washing behaviour in schools (reported and observed) and at home (reported only) by administering structured questionnaires and records respectively at baseline and 12 months after deworming 2. Intensity (worm egg count) of ascariasis and trichuriasis infections is measured by microscopy, counting helminth ova in samples of about 2 grams, at baseline and 12 months after deworming 3. Levels of hand contamination with worm eggs and E. coli bacteria is measured by a previously validated concentration procedure and microscopy, applied to hand-rinse samples, obtained at 12 months after deworming 4. Prevalence and intensity of hookworm infection is measured by microscopy at baseline and 12 months after deworming	—

Measure

Time frame

1. Hand-washing behaviour in schools (reported and observed) and at home (reported only) by administering structured questionnaires and records respectively at baseline and 12 months after deworming 2. Intensity (worm egg count) of ascariasis and trichuriasis infections is measured by microscopy, counting helminth ova in samples of about 2 grams, at baseline and 12 months after deworming 3. Levels of hand contamination with worm eggs and E. coli bacteria is measured by a previously validated concentration procedure and microscopy, applied to hand-rinse samples, obtained at 12 months after deworming 4. Prevalence and intensity of hookworm infection is measured by microscopy at baseline and 12 months after deworming

—

Countries

Tanzania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 22, 2026