Identifying the factors that can improve the quality of flexible telescopic examination (endoscopy) of gullet, stomach and small bowel by analysing the information of the patients who were diagnosed with upper gastrointestinal cancer and had endoscopy prior to diagnosis and by analysing the national endoscopic database

Identifying procedure-adjusted quality indicators for upper gastrointestinal endoscopy from multivariable analysis of cohorts with post-endoscopy upper gastrointestinal cancer (POUGIC) in the National Endoscopy Database (NED)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN44918181

Enrollment

360000

Registered

2023-12-27

Start date

2020-11-02

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper gastrointestinal cancer Cancer

Interventions

The researchers will request unidentifiable information for the patients who were diagnosed with upper gastrointestinal cancers in the UK from 01/01/2009 to 31/12/2018 from National Cancer Registratio

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. All patients 18 years of age and over at diagnosis, who are diagnosed with oesophageal, gastric and duodenal cancers from 01/01/2009 to 31/12/2018, identified in National Cancer Registration and Analysis Service (NCRAS) 2. All endoscopies performed and recorded in Hospital Episode Statistics (HES) in England between 01/01/2006 to 31/12/2018 in patients identified with oesophageal, gastric and duodenal cancer from NCRAS data 3. 200,000 upper gastrointestinal endoscopies performed in the UK and recorded in National Endoscopy Database (NED)

Exclusion criteria

Exclusion criteria: 1. Paediatric population (<18 years) 2. Residents outside England

Design outcomes

Primary

Measure	Time frame
Evidence-based procedure-adjusted quality indicators for upper gastrointestinal endoscopy which can reduce the risk (odds) of post endoscopy upper gastrointestinal cancer, identified by analysing linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018 and using the National Endoscopy Database (NED) for 01/10/2021 to 31/12/2021	—

Measure

Time frame

Evidence-based procedure-adjusted quality indicators for upper gastrointestinal endoscopy which can reduce the risk (odds) of post endoscopy upper gastrointestinal cancer, identified by analysing linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018 and using the National Endoscopy Database (NED) for 01/10/2021 to 31/12/2021

—

Secondary

Measure	Time frame
1. Factors associated with post endoscopy upper gastrointestinal cancers (POUGIC) measured using linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018 2. Rates of POUGIC cases across NHS hospitals measured using linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018	—

Measure

Time frame

1. Factors associated with post endoscopy upper gastrointestinal cancers (POUGIC) measured using linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018 2. Rates of POUGIC cases across NHS hospitals measured using linked National Cancer Registration and Analysis Service (NCRAS) database and Hospital Episode Statistics (HES) for 01/01/2009 to 31/12/2018

—

Countries

England, United Kingdom

Contacts

Public ContactNigel Trudgill

nigel.trudgill@nhs.net+44 (0)1215072577

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026