First-episode psychosis
Conditions
Interventions
Participants are randomly allocated in a 1:1 ratio to either a Compensatory Cognitive Training (CCT) intervention arm or an enhanced Recreational Therapy control arm using computer-generated block ran
Sponsors
Lagos State University College of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: 1. DSM-5 diagnosis of a primary psychotic disorder (schizophrenia, schizophreniform, schizoaffective, delusional, brief psychotic, substance-induced, or affective psychosis with psychotic features) with onset within the previous 5 years, confirmed using MINI 7.0 2. Age 18–30 years inclusive 3. Objective cognitive impairment documented on the Brief Assessment of Cognition in Schizophrenia (BACS), defined as composite score =0.5 SD below age/education-adjusted norms 4. Fluent in English or Nigerian Pidgin sufficient to participate in group sessions and complete assessments 5. Mental capacity to provide informed consent and follow study procedures 6. Clinically stable (no psychiatric admission in previous 4 weeks; no major antipsychotic dose change in previous 2 weeks) 7. Receiving care at one of the participating hospitals
Exclusion criteria
Exclusion criteria: 1. Dementia, intellectual disability or primary organic brain disorder 2. Traumatic brain injury with persistent cognitive sequelae or other neurological disease affecting cognition 3. Current substance dependence (excluding nicotine) 4. Severe comorbid medical illness preventing group attendance 5. High imminent suicide/homicide risk or acute agitation requiring intensive intervention 6. Very severe acute psychotic symptoms unsuitable for group participation 7. Residence outside facility catchment areas without reliable transport 8. Current participation in another cognitive intervention trial 9. Previous participation in formal cognitive remediation within past 12 months
Countries
Nigeria
Contacts
Public ContactAbiodun Adewuya
Outcome results
None listed