The effectiveness of advanced platelet-rich fibrin in comparison with leukocyte-platelet-rich fibrin on outcome after dentoalveolar surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN44767135

Enrollment

Registered

2020-10-14

Start date

2020-01-19

Completion date

Unknown

Last updated

2021-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain and soft tissue healing after tooth extraction Oral Health

Interventions

Patients are divided by stratified randomization into three groups: Group ?: 20 patients treated with advanced platelet-rich fibrin after tooth extraction Group ??: 20

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Able to speak and communicate in Arabic and English 2. Single posterior tooth extraction 3. Aged 18–50 4. Male or female 5. Surgical or extraction site free of active infection 6. Free of significant systemic disease

Exclusion criteria

Exclusion criteria: 1. Patients undergoing chemotherapy and radiotherapy 2. Mentally retarded 3. Medical condition affecting wound healing such as uncontrolled diabetes mellitus 4. Pregnant women

Design outcomes

Primary

Measure	Time frame
1. Pain measured using a visual analogue scale (VAS) after 1 and 2 days 2. Number of analgesics taken, recorded after 6, 12, 18 and 24 hours 3. Soft tissue healing measured using the Landry Wound Healing Index (LWHI) after 1 and 2 weeks	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Saudi Arabia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026