Immediate delivery versus expectant care in women with ruptured membranes close to term

Conditions

Preterm prelabour rupture of membranes Pregnancy and Childbirth Preterm labour

Morris JM, Roberts CL, Bowen JR, Patterson JA, Bond DM, Algert CS, Thornton JG, Crowther CA, PPROMT Collaboration.

2015-11-10100 citations

Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial.

van der Ham DP, Vijgen SM, Nijhuis JG, van Beek JJ, Opmeer BC, Mulder AL, Moonen R, Groenewout M, van Pampus MG, Mantel GD, Bloemenkamp KW, van Wijngaarden WJ, Sikkema M, Haak MC, Pernet PJ, Porath M, Molkenboer JF, Kuppens S, Kwee A, Kars ME, Woiski M, Weinans MJ, Wildschut HI, Akerboom BM, Mol BW, Willekes C, PPROMEXIL trial group.

2012-04-2474 citations

10.1371/journal.pmed.1001208

Induction of labour versus expectant management in women with preterm prelabour rupture of membranes between 34 and 37 weeks (the PPROMEXIL-trial).

van der Ham DP, Nijhuis JG, Mol BW, van Beek JJ, Opmeer BC, Bijlenga D, Groenewout M, Arabin B, Bloemenkamp KW, van Wijngaarden WJ, Wouters MG, Pernet PJ, Porath MM, Molkenboer JF, Derks JB, Kars MM, Scheepers HC, Weinans MJ, Woiski MD, Wildschut HI, Willekes C.

2007-07-0629 citations

10.1186/1471-2393-7-11

Interventions

Immediate delivery (within 24 hours) versus expectant management. Added as of 13/02/2009: The duration of follow-up is 4 months post estimated date of confinement (EDC) or the baby's due delivery da

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Current inclusion criteria as of 12/02/2009: Singleton pregnancies, with confirmed ruptured membranes from 34 weeks to 36 weeks and 6 days gestation. Previous inclusion criteria: Pregnant women with preterm prelabour rupture of the membranes at 34 - 36 weeks

Exclusion criteria

Exclusion criteria: Women who are in established labour, have clinical evidence of chorioamnionitis or other indications for immediate delivery such as meconium staining of the liquor or an antepartum haemorrhage or any other contraindication to expectant management will be excluded from the study. The presence of Group B streptococcus on urine or genital tract culture will not be a specific indication for exclusion from the study.

Design outcomes

Primary

Measure	Time frame
Neonatal sepsis	—

Secondary

Measure	Time frame
1. Secondary infant outcomes: 1.1. Respiratory distress 1.2. Perinatal mortality 1.3. Duration of stay in special care unit 1.4. Duration of stay in hospital 1.5. Birth weight 1.6. Apgar score at 5 minutes 1.7. Any assisted ventilation 1.8. Early infant development 2. Secondary maternal outcomes: 2.1. Chorioamnionitis 2.2. Endometritis treated with antibiotics 2.3. Post-partum fever 2.4. Placental abruption 2.5. Induction of labour 2.6. Failed induction of labour 2.7. Caesarean section 2.8. Assisted vaginal delivery 2.9. Maternal satisfaction 2.10. Views of care 2.11. Duration of hospitalisation 2.12. Antenatally and postnatally, time to fully establish breast feeding 2.13. Maternal emotional wellbeing 2.14. Anxiety and depression	—

Measure

Time frame

1. Secondary infant outcomes: 1.1. Respiratory distress 1.2. Perinatal mortality 1.3. Duration of stay in special care unit 1.4. Duration of stay in hospital 1.5. Birth weight 1.6. Apgar score at 5 minutes 1.7. Any assisted ventilation 1.8. Early infant development 2. Secondary maternal outcomes: 2.1. Chorioamnionitis 2.2. Endometritis treated with antibiotics 2.3. Post-partum fever 2.4. Placental abruption 2.5. Induction of labour 2.6. Failed induction of labour 2.7. Caesarean section 2.8. Assisted vaginal delivery 2.9. Maternal satisfaction 2.10. Views of care 2.11. Duration of hospitalisation 2.12. Antenatally and postnatally, time to fully establish breast feeding 2.13. Maternal emotional wellbeing 2.14. Anxiety and depression

—

Countries

Argentina, Australia, New Zealand, Norway, Poland, Romania, South Africa, United Kingdom

Outcome results

None listed