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The effectiveness of cognitive remediation therapy (CRT) for patients with schizophrenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN44277627
Enrollment
Unknown
Registered
2004-01-23
Start date
2000-11-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and behavioural disorders: Schizophrenia and other psychoses Mental and Behavioural Disorders Schizophrenia

Interventions

1. Cognitive remediation therapy 2. Standard care

Sponsors

NHS R&D Regional Programme Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. In contact with local psychiatric services for at least two years 2. Diagnosis of schizophrenia based on The Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSMIV) 3. Evidence of some cognitive difficulties (rated as poor on either memory or cognitive flexibility) 4. Evidence of social functioning problems (scored on at least one problem on Social Behaviour Scale)

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
All have been chosen for their good reliability and validity and use in this population of patients. i. Cognitive outcomes - the results of neuropsychological tests (see plan of investigation for details) ii. Social Behaviour - DEX independent questionnaire, Social Behaviour Schedule and Test of Grocery Skills iii. Symptom outcome - PANNS iv. Quality of Life - MANSA v. Self esteem - Rosenberg self esteem schedule vi. Service contact - Client Service Receipt Inventory Process measures - These forms allow ratings of the level of performance achieved in each session, with reference to the individual tasks carried out in the session as well as at the end of each module. They have established inter-rater reliability as well as face validity.

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026