Skip to content

A trial to assess the effectiveness of a novel mosquito insecticide dissemination device to reduce infection by dengue virus

Efficacy of the In2Care® auto-dissemination device for reducing dengue transmission: study protocol for a parallel two-armed cluster randomised trial in the Philippines

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN44272773
Enrollment
4600
Registered
2019-01-31
Start date
2019-03-01
Completion date
Unknown
Last updated
2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dengue virus infection Infections and Infestations Dengue

Interventions

Cluster sites (46) will be selected from within Puroks (smallest administrative unit) that had been classfied according to previous dengue incidence (previous 5 years) and population density. An inter

Sponsors

Institut Pasteur
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 6-16 years old, male and female individuals 2. Parent/guardian informed consent for the child’s participation in the study 3. For children > 7 years old, required assent for his/her participation in the study

Exclusion criteria

Exclusion criteria: 1. Children <6 years old 2. Children with known concomitant pathology(ies) at the time of the consent as indicated by parent/guardian 3. Refusal to participate

Design outcomes

Primary

MeasureTime frame
Sero-conversion to dengue virus, measured using IgG ELISA. The three samples (baseline, during after month 2 of intervention) and after intervention (month 5) from each individual are analysed together at the end of each year's intervention period.

Secondary

MeasureTime frame
Adult mosquito densities: Gravid Aedes traps weekly count data analysed at end of intervention period of each year

Countries

Philippines

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 3, 2026