Pre-operative chemotherapy for cancer of the oesophagus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43987580

Enrollment

800

Registered

2001-02-28

Start date

1992-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Cancer Oesophageal cancer

Interventions

1. One group receives pre-operative chemotherapy followed by surgery 2. The other group = Control group receives surgery alone

Eligibility

Inclusion criteria

Inclusion criteria: 1. Tumour considered resectable 2. No evidence of cervical lymph node involvement or metastases 3. Creatinine clearance =60 ml/min 4. Total white blood cell count =3.5 x 109l 5. Platelet count =100 x 109l 6. No indication for urgent resection 7. No previous chemotherapy, radiotherapy or surgery for current oesophageal cancer 8. No other previous or concomitant malignant disease

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Survival time	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026