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The effect of resistance training and aerobic exercise on vascular stiffness, novel cardiovascular risk markers, aerobic capacity, muscle strength and incidence of complications in the first year of renal transplantation. A randomised controlled study

The effect of resistance training and aerobic exercise on vascular stiffness, novel cardiovascular risk markers, aerobic capacity, muscle strength and incidence of complications in the first year of renal transplantation. A randomised controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN43892586
Enrollment
60
Registered
2014-07-31
Start date
2013-03-01
Completion date
Unknown
Last updated
2017-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Renal disorders

Interventions

Aerobic training: AT will predominantly be on stationary exercise cycles at 80% hear rate reserve. Resistance Training: Resistance training will use RT machines training large muscle groups (e.g. benc
Study Entry : Single Randomisation only

Sponsors

King's College Hospital NHS Foundation Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All patients undergoing renal transplant 2. Male or female 3. Aged >18 years 4. Written informed consent; Target Gender: Male & Female ; Lower Age Limit 18 years

Exclusion criteria

Exclusion criteria: 1. Requiring support for ambulation less than 20m 2. Vasculitis 3. Proliferative diabetic retinopathy, 4. Severe osteodystophy 5. Uncontrolled diabetes 6. Psychiatric illness, including anxiety, mood and untreated eating disorders 7. Infection or course of antibiotics within the last month

Design outcomes

Primary

MeasureTime frame
Pulse Wave Velocity (PWV); Timepoint(s): Baseline, 12 weeks and 12 months—

Secondary

MeasureTime frame
1. CVD biomarkers - Fetuin A, TNF receptor 2, IL6, HS CRP; Timepoint(s): Baseline, 12 weeks and 12 months 2. Duke's Activity Status Index; Timepoint(s): Baseline and 12 weeks 3. Muscle strength (myometer); Timepoint(s): baseline and 12 weeks 4. Resting heart rate and blood pressure; Timepoint(s): baseline, 12 weeks and 12 months 5. Sit to stand 60; Timepoint(s): baseline and 12 weeks 6. VO2peak; Timepoint(s): baseline, 12 weeks and 12 months—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 27, 2026