Endometrial aspiration before or after Saline Infusion Sonography (SIS) in case of abnormal uterine bleeding: effect on specimen quality

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43875039

Enrollment

120

Registered

2007-06-27

Start date

2006-09-01

Completion date

Unknown

Last updated

2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormal uterine bleeding, Saline Infusion Sonography (SIS), endometrial aspiration Urological and Genital Diseases Uterine bleeding

Interventions

Saline Infusion Sonography (SIS) and endometrial aspiration are performed with the same catheter in one session. Patients are either allocated to aspiration and subsequent SIS, or to the reverse order

Eligibility

Inclusion criteria

Inclusion criteria: Patients with abnormal uterine bleeding.

Exclusion criteria

Exclusion criteria: 1. Pelvic Inflammatory Disease (PID) 2. Cervical cancer

Design outcomes

Secondary

Measure	Time frame
Reliability of video SIS-images. The SIS was performed in the same session and was recorded on video.	—

Primary

Measure	Time frame
Quality assessment of aspiration specimen by pathologist. Evaluation of the biopsy was performed by the pathologist immediately after taking the endometrial biopsy.	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026