Wean earlier and automatically with new technology: a multicentre, pilot randomised controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43760151

Enrollment

Registered

2006-01-30

Start date

2006-05-30

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Weaning intubated adults from invasive mechanical ventilation Respiratory Invasive mechanical ventilation

Interventions

Automatic (computer-driven) weaning versus protocolized weaning

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are invasively ventilated for at least 24 hours

Exclusion criteria

Exclusion criteria: 1. Age < 16 years 2. Tracheotomy 3. Pregnancy 4. Do not intubate (DNI) or do not resuscitate (DNR) patients 5. Planned extubation on the day of study inclusion 6. Planned surgery or procedures within 48 hours of randomization

Design outcomes

Primary

Measure	Time frame
Compliance with the weaning and sedation protocols	—

Secondary

Measure	Time frame
1. Acceptance of the weaning and sedation protocols 2. Weaning and Intensive Care Unit (ICU) related-complications 3. Time to successful completion of a Single Breath Test (SBT) and extubation	—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 2, 2026