Congestive heart failure Circulatory System Congestive heart failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Heart failure patients aged greater than 60 years 2. New York Heart Association (NYHA) greater than or equal to II 3. CHF hospitalisation within last year 4. NT-BNP level greater than 800 pg/ml (greater than or equal to 75 years), 400 pg/ml (60 - 74 years)
Exclusion criteria
Exclusion criteria: 1. Serum creatinine greater than 220 µmol/l 2. Valve disease needing surgery 3. Disease other than cardiovascular limiting life-expectancy less than 3 years 4. No informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. All cause hospitalisation free survival after 18 months 2. Quality of life after 18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Primary endpoints after 12 months 2. Components of primary endpoints 3. Overall costs and use of health care resources 4. Cost-effectiveness 5. Patients' preferences regarding treatment 6. Effects of baseline characteristics on outcome 7. Prediction of tolerability and effect of medication | — |
Countries
Switzerland