Effects of tranexamic acid in total knee arthroplasty - pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43363116

Enrollment

Registered

2005-09-30

Start date

2000-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Total knee arthroplasty Surgery Total knee arthroplasty

Interventions

Prospective, randomised controlled trial of 15 mg/ kg tranexamic acid v equivalent volume of normal saline given iv prior to tourniquet release during TKA

Eligibility

Inclusion criteria

Inclusion criteria: 15 patients, 15 control patients of any age who are planned to have total knee arthroplasty

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
1. Blood loss in the first 48 hours post op 2. Transfusion requirements 3. Screen-detected DVT	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026