Epidural steroid injection in chronic lumbar back pain: a cross-over, single-blinded study of methyl-prednisolone 80mg versus methyl-prednisolone 40mg

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43299460

Enrollment

Registered

2007-09-28

Start date

2006-05-24

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases: Low back pain Musculoskeletal Diseases Low back pain

Interventions

1. 80mg methyl-prednisolone repeated three months later with 40mg dose 2. 40mg methyl-prednisolone repeated three months later with 80mg dose

Eligibility

Inclusion criteria

Inclusion criteria: Patients attending Nottingham City Hospital Day Case Unit, with chronic back pain who are presenting for repeat epidural steroid injection as part of their chronic pain management programme.

Exclusion criteria

Exclusion criteria: 1. Blood clotting disorder 2. Anticoagulant (Warfarin) use

Design outcomes

Primary

Measure	Time frame
Evidence that a reduced dose of methyl-prednisolone given epidurally does not cause a significant worsening of the primary outcome measure ie the Oswestry Low Back Pain Disability Index.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026