Investigating the role of advanced MR imaging in assessing patients with trapped nerves in the neck

Assessing cervical foraminal stenosis: volumetric MRI study in patients with cervical brachialgia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN43263110

Enrollment

Registered

2020-10-19

Start date

2021-04-01

Completion date

Unknown

Last updated

2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical foraminal stenosis leading in patients with radiculopathy Musculoskeletal Diseases Radiculopathy

Interventions

Pre-operative patients will be recruited from surgical waiting lists with symptomatic cervical brachialgia for at least six weeks. An additional three-dimensional volumetric MRI scan of the cervical

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age over 18 years 2. Diagnosis of brachialgia 3. Able to provide fully informed written consent 4. Able to lie flat for 1 hour in an MRI scanner 5. Awaiting either an anterior cervical discectomy or a posterior cervical foraminotomy for brachialgia 6. Females of childbearing age must be using effective contraception 7. Sufficient understanding of English to participate in the trial

Exclusion criteria

Exclusion criteria: 1. Cervical myelopathy 2. Radiological evidence of cord compression 3. History of cervical trauma 4. Evidence of suspected or histologically proven tumour 5. Previous cervical spine surgery 6. Non-MRI compatible implantable device e.g. pacemaker 7. Unable to have MRI scan due to claustrophobia 8. Female participants must not be pregnant and if of childbearing age must be using adequate contraception

Design outcomes

Primary

Measure	Time frame
Self-rated disability assessed using Neck Disability Index (NDI) at 6 weeks post-surgery	—

Secondary

Measure	Time frame
1. Self-rated disability assessed Neck Disability Index (NDI) at 1 day post-surgery 2. Pain intensity assessed using Numerical Rating Scales for neck and upper limb pain 1 day and 6 weeks post-surgery. 3. Neuropathic pain assessed using PainDETECT at day 0 and at 1 day and 6 weeks post-surgery 4. Extent and severity of spinal cord and upper limb functional impairment assessed using a restricted version of the ASIA score at the pre-operative assessment and at 1 day and 6 weeks post-surgery 5. Complications occurring during the initial trial operative procedure and postoperative complications recorded up to 6 weeks post-surgery	—

Measure

Time frame

1. Self-rated disability assessed Neck Disability Index (NDI) at 1 day post-surgery 2. Pain intensity assessed using Numerical Rating Scales for neck and upper limb pain 1 day and 6 weeks post-surgery. 3. Neuropathic pain assessed using PainDETECT at day 0 and at 1 day and 6 weeks post-surgery 4. Extent and severity of spinal cord and upper limb functional impairment assessed using a restricted version of the ASIA score at the pre-operative assessment and at 1 day and 6 weeks post-surgery 5. Complications occurring during the initial trial operative procedure and postoperative complications recorded up to 6 weeks post-surgery

—

Countries

England, United Kingdom

Contacts

Public ContactSimon Thomson

S.Thomson@leeds.ac.uk+44 (0)113 3928567

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026