A comparison of intermittent aortic cross clamping and intermittent aortic warm blood cardioplegia for myocardial protection during coronary artery bypass surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43177829

Enrollment

Registered

2005-09-30

Start date

2004-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Coronary artery bypass grafting (CABG) Surgery Coronary artery bypass grafting (CABG)

Interventions

40 patients undergoing elective CABG will randomly be allocated into two groups of 20 patients each, to receive either intermittent cross clamp with fibrillation (XCF) or intermittent warm blood cardi

Following institution of cardiopulmonary bypass, but prior to the application of an aortic cross clamp with resultant myocardial ischaemia

30,60,90,120 minutes and 4,6,8,12,24,28 hours following final release of the aortic cross clamp. The blood will be centrifuged for serum, which will be stored frozen at -70C until batch analysis. The

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective CABG

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026