An exploratory randomised controlled trial of a CBT-based recovery intervention for early bipolar disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN43062149

Enrollment

Registered

2011-04-08

Start date

2011-02-09

Completion date

Unknown

Last updated

2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar affective disorder Mental and Behavioural Disorders Bipolar disorder

Interventions

1. Recovery focussed CBT 2. The intervention has been developed through collaboration between a multidisciplinary group of mental health professionals and service users with experience of bipolar diso

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Individuals who have received a clinical diagnosis of bipolar disorder or who have experienced a first episode of mania within the last 5 years 2. Aged between 18-65 3. Can provide written informed consent 4. Can communicate in English 5. Target Gender: Male & Female

Exclusion criteria

Exclusion criteria: 1. Individuals who are currently experiencing or have experienced within the last month, an acute episode of major depression or mania 2. Individuals referred into the study during an acute episode will wait until they have been out of episode for one month before entering the study. Nevertheless, it is expected that most participants will have subsyndromal mood symptoms.

Design outcomes

Primary

Measure	Time frame
1. Time to bipolar relapse 2. Timepoint(s): assessed every 3 months from baseline	—

Secondary

Measure	Time frame
1. Beck Depression Inventory score - Timepoint(s): baseline, 6 months, 12 months, 18 months 2. Hamilton depression rating scale score - Timepoint(s): baseline, 6 months, 12 months, 18 months 3. Hypomanic Interpretations Questionnaire - Timepoint(s): baseline, 6 months, 12 months, 18 months 4. Internal States Scale score - Timepoint(s): baseline, 6 months, 12 months, 18 months 5. Interpretation of Depression Questionnaire - Timepoint(s): baseline, 6 months, 12 months, 18 months 6. Mania Rating Scale - Timepoint(s): baseline, 6 months, 12 months, 18 months 7. Personal and Social Performance Scale - Timepoint(s): baseline, 6 months, 12 months, 18 months; 8. Post Traumatic Growth Inventory - Timepoint(s): baseline, 6 months, 12 months, 18 months 9. Self reported recovery score - Timepoint(s): baseline and every 6 months; 10. Self-Esteem Rating Scale (Short Form) - Timepoint(s): baseline, 6 months, 12 months, 18 months 11. The Brief Quality of Life in Bipolar Disorder - Timepoint(s): baseline, 6 months, 12 months, 18 months	—

Measure

Time frame

1. Beck Depression Inventory score - Timepoint(s): baseline, 6 months, 12 months, 18 months 2. Hamilton depression rating scale score - Timepoint(s): baseline, 6 months, 12 months, 18 months 3. Hypomanic Interpretations Questionnaire - Timepoint(s): baseline, 6 months, 12 months, 18 months 4. Internal States Scale score - Timepoint(s): baseline, 6 months, 12 months, 18 months 5. Interpretation of Depression Questionnaire - Timepoint(s): baseline, 6 months, 12 months, 18 months 6. Mania Rating Scale - Timepoint(s): baseline, 6 months, 12 months, 18 months 7. Personal and Social Performance Scale - Timepoint(s): baseline, 6 months, 12 months, 18 months; 8. Post Traumatic Growth Inventory - Timepoint(s): baseline, 6 months, 12 months, 18 months 9. Self reported recovery score - Timepoint(s): baseline and every 6 months; 10. Self-Esteem Rating Scale (Short Form) - Timepoint(s): baseline, 6 months, 12 months, 18 months 11. The Brief Quality of Life in Bipolar Disorder - Timepoint(s): baseline, 6 months, 12 months, 18 months

—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 25, 2026