Scabies Infections and Infestations
Conditions
Interventions
Adults presenting to routine (public) health facilities with suspicion of scabies first perform self-sampling consisting of skin scrapings and a subsequent skin swab. Sampling (skin scrapings and subs
Sponsors
Radboud University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 18 years or older 2. Attending a participating scabies outpatient clinic or dermatology outpatient clinic with suspicion of scabies 3. Providing written informed consent
Exclusion criteria
Exclusion criteria: 1. Individuals not speaking or understanding the Dutch or English language 2. Individuals who have been diagnosed with scabies in the last four weeks and have started treatment 3. Individuals who have used ivermectin for other diagnoses than scabies in the last 6 weeks 4. Individuals younger than 18 years 5. Individuals with immunosuppressive conditions 6. Any other condition, finding or situation which, in the opinion of the investigator, may significantly increase the risk to the individual because of participation in the study, affect the ability of the individual to participate in the study or impair interpretation of the study data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positivity of self-collected samples (defined as qPCR- and/or microscopy-positive on self-collected skin scrapings and/or self-collected skin swab) compared with positivity of professionally collected samples (defined as qPCR- and/or microscopy-positive on professionally collected skin scrapings and/or professionally collected skin swab); all samples are collected at baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Positivity of skin scrapings (defined as qPCR- and/or microscopy-positive on self-collected and/or professionally collected skin scrapings) compared with positivity of skin swabs (defined as qPCR-positive on self-collected and/or professionally collected skin swabs) ; all samples are collected at baseline 2. Positivity by qPCR (defined as qPCR-positive on self-collected and/or professionally collected skin scrapings) compared with positivity by microscopy (defined as microscopy-positive on self-collected and/or professionally collected skin scrapings); all samples are collected at baseline | — |
Countries
Netherlands
Contacts
Public ContactMatthew McCall
Outcome results
None listed