Investigation of continence, sexual- and bowel function after radical surgery for bladder cancer

Functional outcomes after radical cystectomy – with emphasis on continence, sexual and rectal function – a prospective study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN42949068

Enrollment

100

Registered

2015-10-07

Start date

2015-01-01

Completion date

Unknown

Last updated

2025-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer treated with radical cystectomy Cancer Bladder cancer

Interventions

Before the radical cystectomy procedure, patients complete a number of questionnaires concerning their sexual function and faecal continence. Additionally, rectal function is measured using manuvolume

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years or over 2. Planned radical cystectomy for bladder cancer

Exclusion criteria

Exclusion criteria: Previous pelvic radiation

Design outcomes

Primary

Measure	Time frame
1. Decline in sexual function measured using IIEF-5 questionnaire (erectile dysfunction) for male participants and FSFI (female sexual dysfunction) questionnaire for female participants before surgery (baseline) and 12 months post-operatively 2. Inontinence measured using the St Mark’s questionnaire (faecal incontinence) before surgery (baseline) and 12 months post-operatively 3. Rectal function is measured by manuvolumetry is measured by maximum closure pressure (MACP) and resting anal sphincter pressure (RASP) before surgery (baseline) and 12 months post-operatively	—

Measure

Time frame

1. Decline in sexual function measured using IIEF-5 questionnaire (erectile dysfunction) for male participants and FSFI (female sexual dysfunction) questionnaire for female participants before surgery (baseline) and 12 months post-operatively 2. Inontinence measured using the St Mark’s questionnaire (faecal incontinence) before surgery (baseline) and 12 months post-operatively 3. Rectal function is measured by manuvolumetry is measured by maximum closure pressure (MACP) and resting anal sphincter pressure (RASP) before surgery (baseline) and 12 months post-operatively

—

Secondary

Measure	Time frame
Rectal function assessed preoperatively and postoperatively after radical cystectomy using transrectal manuvolumetry and transrectal ultrasound, before surgery (baseline) and 12 months post-operatively.	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026