Modulation of ischaemic induced cardiac dysfunction by remote pre-conditioning

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN42864201

Enrollment

Registered

2003-09-12

Start date

2002-04-02

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Single vessel coronary disease Circulatory System Chronic ischaemic heart disease

Interventions

Myocardial ischaemia is common in patients with coronary artery disease (CAD) and may be asymptomatic and occur during everyday life. Brief episodes of demand ischaemia, where the increase in coronary

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Added July 2008: 1. Able to consent 2. Age >18 3. Coronary artery disease 4. Normal left ventricular function

Exclusion criteria

Exclusion criteria: Added July 2008: 1. Diabetes mellitus 2. Valvular heart disease 3. Permanent pacemaker 4. Left bundle branch block (LBBB) on electrocardiogram (ECG) 5. Myocardial infarction in the preceding 3 months 6. Not in sinus rhythm or taking nicorandil or glibenclamide medication

Design outcomes

Primary

Measure	Time frame
Added July 2008: Change in ejection fraction after remote preconditioning, compared to baseline.	—

Secondary

Measure	Time frame
Added July 2008: 1. Segmental LV wall tissue velocities 2. Rate pressure product 3. ECG ST deviation and chest pain score after remote preconditioning, compared to baseline	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 1, 2026