Nasopharyngeal carcinoma screening Cancer
Conditions
Interventions
Study design: Prospective cohort study.
Study population: Local residents aged 30–69 years in Zhongshan, Guangdong, who participated in NPC screening from January 1 to December 31, 2026
inclusion requires no history of NPC and signed informed consent.
process:
Collect serological and epidemiological data (gender, age, family history) of medium- and high-risk populations
Further stratify risk via the HD model to determine follow-up measures (nasopharyngoscopy or serological follow-up).
Outcome analysis: Calculate core diagnostic indicators
compare efficacy with serological screening alone
conduct cost-effectiveness analysis (cost-effectiveness ratio [CER], incremental cost-effectiveness ratio [ICER]).
Sponsors
Jinan University
Eligibility
Sex/Gender
All
Age
30 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1. Registered population aged 30–69 years in the screening area (Zhongshan City) 2. No previous history of nasopharyngeal carcinoma 3. Participants who agreed to sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiac, cerebral, hepatic, pulmonary or renal diseases 2. Patients with severe immune system diseases 3. Patients currently receiving glucocorticoid or immunosuppressive therapy 4. Individuals with poor mental status and impaired consciousness
Countries
China
Contacts
Public ContactShuixing Zhang
Outcome results
None listed