Skip to content

The tolerability and efficacy of Hyalubrix® in osteoarthritis

A prospective observational study of the tolerability and efficacy of injectable hyaluronic acid therapy (Hyalubrix®) in osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN42690497
Enrollment
1300
Registered
2009-07-21
Start date
2006-08-28
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis Musculoskeletal Diseases Polyarthrosis

Interventions

Four visits were scheduled: Visit one: enrolment and start of therapy Visit two: during study treatment Visit three: during study treatment Visit four: patient's final evaluation, 2 weeks from third

Sponsors

Fidia Farmaceutici S.p.A. (Italy)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients suffering from degenerative or mechanical arthropathies who were candidates for being treated with Hyalubrix® 2. Patients aged 18 years or older, either sex 3. Patients who signed informed consent form

Exclusion criteria

Exclusion criteria: 1. Infections located in the body area to be treated 2. Established sensitivity to hyaluronic acid or to other components of the product

Design outcomes

Primary

MeasureTime frame
Adverse event notification. Timepoints: Visit 0: at baseline Visit 2: one week after baseline Visit 3: one week after visit 2 Final visit: two weeks after visit 3

Secondary

MeasureTime frame
1. Evaluation of the medical device performance on pain during motion and at rest, determined by VAS and HAQ 2. Quality of life evaluation (by means of EuroQoL) Timepoints: Visit 0: at baseline Visit 2: one week after baseline Visit 3: one week after visit 2 Final visit: two weeks after visit 3

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026