Topic: Stroke
Conditions
Interventions
In both study groups at the start of the study and after 12 months a 24 hour blood pressure recording will be taken.
At the start of the study and after 12 months pulse wave velocity
Sponsors
Norfolk and Norwich University Hospital NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult patients admitted to the participating centre with confirmed stroke (first/recurrent) or TIA will be considered for the trial. Inclusion criteria 1. Normal cognition (MoCA score >=26) and no evidence of moderate/severe depression (GDS =26) will be informed of their normal cognition status and will be managed routinely by the clinicians with regards to their risk factors. They will be invited to participate in the observational study (defined as GROUP O). If they agree, written informed consent will be obtained. 2. Intermediate cognition (MoCA score 20-25). Patients with MoCA score of 20-25 will be informed of their cognitive status and be invited to participate in the feasibility trial. Those who agree and provide written informed consent will be randomised into one of two groups; control arm (GROUP C) and intervention arm (GROUP I).
Exclusion criteria
Exclusion criteria: Those with following conditions will be excluded on ethical grounds: 1. Severe cognitive deficit (MoCA <20). Patients with severe cognitive deficit (MoCA <20) will be informed of their cognition status and their GP will also be informed for further appropriate action. Hospital teams will be liaised with and an appropriate level of community support at discharge will be organised. By doing so, we hope that the anxiety of knowing their cognitive deficit will be reduced. They will be excluded from the trial as it is not ethical to include them in the feasibility stage. 2. Established Dementia / MoCA score <20 3. Moderate/severe depression 4. Life expectancy <1 yr (e.g. severe stroke/terminal cancer) 5. Unable to perform MoCA (aphasic patients)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Cognition and in CV risk factors over 1 year follow-up; Timepoint(s): Changes in Cognition and in CV risk factors over 1 year follow-up | — |
Countries
United Kingdom
Contacts
Public ContactJohn Potter
Outcome results
None listed