Skip to content

Comparative study of postoperative pain and healing capacity of two endodontic sealers (AH Plus and NeoSealer Flo)

Randomised clinical trial: Effect of AH Plus and Neosealer Flo on postoperative pain and healing of periapical lesions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN42633118
Enrollment
80
Registered
2025-02-18
Start date
2024-03-14
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root canal treatment Oral Health

Interventions

Patients will be treated at the Centre for Dental Innovation and Specialities of Universidad Alfonso X el Sabio, Madrid, Spain. Participants will be randomly assigned into two groups using the online

Sponsors

University Alfonso X el sabio
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients over 18 years of age, cooperative and in good general health (ASA class I or II). 2. Have at least one tooth requiring endodontic treatment and provide informed consent for both the treatment and study participation. 3. The resulting RCTs will have to meet the following criteria: 3.1. Root canal obturation within 2 mm of the radiographic apex. 3.2. Absence of voids on the final radiograph.

Exclusion criteria

Exclusion criteria: 1. Teeth with open apices. 2. Coronal cracks extending into the root canal. 3. Root perforations. 4. Severe periodontal disease. 5. Vertical root fractures.

Design outcomes

Primary

MeasureTime frame
1. Postoperative pain is measured using Visual Analog Scale (VAS) at baseline (prior to treatment), 24 hours postoperative, 48 hours postoperative, and 72 hours postoperative 2. State of the lesion is measured using preoperative radiograph at the diagnostic phase and at the 6 month follow-up

Secondary

MeasureTime frame
1. Cementum extrusion is measured using visual inspection at the final radiograph of the endodontic treatment

Countries

Spain

Contacts

Public ContactJuan Manuel Aragoneses Llamas
jaraglam@uax.es+34 913273262

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026