Study of oral retinol, with or without medical sun protection, in patients with actinic keratosis

Efficacy and safety of oral retinol, alone or combined with medical photoprotection, in patients with actinic keratosis: a randomized, controlled, prospective, multicentric study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN42565762

Enrollment

105

Registered

2026-05-18

Start date

2023-04-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Actinic keratosis (AK) Skin and Connective Tissue Diseases

Interventions

Participants were randomized into three groups using a computer-generated allocation sequence. The patients were allocated across three treatment groups in a 1:1:1 ratio. Group A received oral vitamin

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Adults aged 18 to 80 years with up to six clinically diagnosed AK lesions

Exclusion criteria

Exclusion criteria: 1. Presence of more than six AK lesions 2. Use of nicotinamide within 6 months prior to enrollment 3. History of skin cancer 4. Organ transplantation 5. Pregnancy or lactation

Countries

Italy

Contacts

Public ContactMassimo Milani

massimo.milani@difacooper.com+39 (0)280030205

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 15, 2026