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The London East Anglia randomised controlled trial for cognitive-behaviour therapy for psychosis: effects of the treatment phase

The London East Anglia randomised controlled trial for cognitive-behaviour therapy for psychosis: effects of the treatment phase

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN42505388
Enrollment
60
Registered
2004-01-23
Start date
1993-01-01
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia and other psychoses Mental and Behavioural Disorders Schizophrenia

Interventions

Participants randomised into the treatment group received up to nine months of individual cognitive behaviour therapy for psychosis. Sessions were conducted weekly initially, and then fortnightly. Par

Sponsors

Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 60 participants who each had one positive and distressing symptom of psychosis that was medication resistant (28 in a treatment group received a cognitive behaviour therapy and 32 a standard care only control condition).

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Measures were taken at baseline of demographic, clinical and cognitive variables. Changes over time were assessed on the Brief Psychiatric Rating Scale and the relationship between potential predictor variables and outcome was investigated using analysis of variance and covariance.

Secondary

MeasureTime frame
Not provided at time of registration

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026