High-risk patients undergoing prolonged surgery Circulatory System High-risk surgical patients
Conditions
Interventions
Therapy consisted of pulmonary artery catheter (PAC)-guided haemodynamic optimisation during the operation and 24 hours postoperatively, using either fluids alone or fluids and dobutamine with the aim
Sponsors
Faculty of Medicine of São José do Rio Preto (FAMERP) Foundation (Brazil)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients older than 18 years old undergoing elective surgeries with greater than or equal to three points according to a risk scoring system adapted from the American College of Cardiology (ACC) or the American Heart Association (AHA) guidelines
Exclusion criteria
Exclusion criteria: 1. Refusal of consent 2. Haemodynamic instability prior to surgery 3. Congestive heart failure 4. Presence of infection 5. Acute myocardial ischaemia prior to enrolment 6. Life expectancy lower than 60 days 7. Disseminated malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of both DO2I optimisation with fluids compared to with fluids and dobutamine on 60-day mortality in high-risk general surgery patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of complications, particularly adverse cardiovascular events. | — |
Countries
Brazil
Outcome results
None listed