Cardiovascular health outcomes. Circulatory System
Conditions
Interventions
Intervention will be performed in one out of two enterprises. There the shift workers are motivated to participate 3 times a week in physical activity of high intensity only lasting for 17 minutes eac
Sponsors
National Institute of Occupational Health
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy volunteers in the two enterprises
Exclusion criteria
Exclusion criteria: Some disorders will disqualify for participation in the study, such as a serious heart condition e.g. blood pressure more than 180/110 and cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aerobic fitness measured continuously with a Cosmed K4b2 breath by breath metabolism analyser (Cosmed Srl, Rome, Italy) and maximal oxygen uptake will be calculated from the highest 30 s averaging interval at the conclusion of the test. Measured at baseline and after 8 weeks and 3 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured at baseline and after 8 weeks and after 3 years (CIMT performed at baseline and final follow-up): 1. Blood pressure and resting heart rate (RHR) are measured on the left arm after five minutes of rest. The measurements are taken three times in intervals of one minute. The average of the last two measurements of both the systolic (sBP) and the diastolic pressure (dBP) will be used in the statistical analysis. Blood pressure and RHR will be measured with BpTRU® (Bp TRU medical devices, Coquitlam, Canada) on both occasions. For a more advanced registration of BP a Sphygmocor XCEL® (Sydney, Australia) devise will be used. All tests will performed using the same device and by the same researchers at the same time of the day both at baseline registration and at follow-ups. 2. Carotid intima-media thickness measured using carotid artery B-mode ultrasound imaging, Vivid iq ®. The participants are investigated about 5-10 minutes the day before the work shift, then again after the shift period and finally at the final follow-up 2-3 years afterwards. The standardized method includes measurement of mean carotid IMT of the common carotid artery (CCA) on the far wall of the CCA at least 5 mm below its end including averaged values IMT-values from both the left and right side. 3. Glycosylated hemoglobin (HbA1c) was collected in EDTA blood. Serum for investigation of lipids (cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and C-reactive protein (CRP) was collected on gel tubes and then centrifuged 35 x 1000 rpm for 15 minutes within 60 minutes after the blood had been drawn from a vein. The tubes were sent by mail to the Department of Medical Biochemistry Oslo University Hospital and analyzed within 24 hours. HbA1c EDTA blood was analyzed with a Tosoh G7 HPLC analyser (Tosoh Bioscience, Inc. San Francisco, CA, USA) which use high performance liquid chromatography as the separation principle. 4. Cholesterol, LDL and HDL in serum analyzed by enz | — |
Countries
Norway
Outcome results
None listed