Can silver diamine fluoride (SDF) reduce the impact on young children of waiting for dental care?

Can silver diamine fluoride reduce negative impacts for young children with dental caries awaiting treatment under general anaesthesia: a feasibility study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN42409963

Enrollment

Registered

2025-03-13

Start date

2025-05-01

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries Oral Health

Interventions

Baseline information will be collected including: age, sex, ethnicity, postcode in order to determine deprivation decile, and free school meal status as a proxy for social deprivation. The number of c

Eligibility

Sex/Gender

All

Age

1 Years to 8 Years

Inclusion criteria

Inclusion criteria: 1. Children, aged 1-8 years with caries in their primary dentition 2. They will have been placed on DGA waiting lists for ‘non-urgent’ (anticipated wait time over 1 month) dental extractions/treatment of carious primary teeth at one of the participating sites 3. Parents will also be included as participants and these pairings will be termed child/parent dyads

Exclusion criteria

Exclusion criteria: 1. Children with medical conditions which preclude SDF treatment

Design outcomes

Primary

Measure	Time frame
1. Numbers of potential participants approached, declined, accepted, recruited is measured using a screening log and recruitment log at baseline 2. Reasons for child/parent dyads declining participation is measured using a screening log at baseline 3. Proportion of child/parent dyads recruited who accept the SDF treatment successfully is measured using a case report form (CRF) at baseline and follow-up visits 4. Feedback about patient, parent, and dental team experiences of SDF application is measured using a 2-item questionnaire at baseline and follow-up visits 5. Numbers of participants retained up to DGA is measured using a CRF and withdrawal log at baseline and follow-up visits 6. Reasons for child/parent dyads withdrawing participation is measured using a CRF and withdrawal log at baseline and follow-up visits 7. Oral health-related quality of life (OHRQoL) is measured using Caries-QC and P-CPQ questionnaires at baseline and within 4 weeks of DGA visit 8. Pain or infection while on the waiting list is measured using a 5-item parental questionnaire via post/text/online/telephone every month while on the waiting list 9. Presence of infection on GA date is measured using a CRF by the local research team on the day of DGA or by reviewing dental records retrospectively 10. Teeth with clinically arrested caries is measured using a CRF at follow-up visits	—

Measure

Time frame

1. Numbers of potential participants approached, declined, accepted, recruited is measured using a screening log and recruitment log at baseline 2. Reasons for child/parent dyads declining participation is measured using a screening log at baseline 3. Proportion of child/parent dyads recruited who accept the SDF treatment successfully is measured using a case report form (CRF) at baseline and follow-up visits 4. Feedback about patient, parent, and dental team experiences of SDF application is measured using a 2-item questionnaire at baseline and follow-up visits 5. Numbers of participants retained up to DGA is measured using a CRF and withdrawal log at baseline and follow-up visits 6. Reasons for child/parent dyads withdrawing participation is measured using a CRF and withdrawal log at baseline and follow-up visits 7. Oral health-related quality of life (OHRQoL) is measured using Caries-QC and P-CPQ questionnaires at baseline and within 4 weeks of DGA visit 8. Pain or infection while on the waiting list is measured using a 5-item parental questionnaire via post/text/online/telephone every month while on the waiting list 9. Presence of infection on GA date is measured using a CRF by the local research team on the day of DGA or by reviewing dental records retrospectively 10. Teeth with clinically arrested caries is measured using a CRF at follow-up visits

—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

England, United Kingdom, Wales

Contacts

Public ContactLaura Timms

l.timms@sheffield.ac.uk+44 114 2159310

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Sep 14, 2026