A study into the effects of 12 weeks of coffee drinking on non-coffee drinkers

A parallel arm study investigating the effects of 12 weeks coffee drinking in non coffee drinkers on glucose metabolism and other risk factors for Type 2 Diabetes Mellitus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN42321643

Enrollment

Registered

2014-01-14

Start date

2013-09-30

Completion date

Unknown

Last updated

2019-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glucose metabolism Nutritional, Metabolic, Endocrine Glucose metabolism

Interventions

Arm 1 (coffee intervention): four cups of coffee per day (made from 2 g instant coffee granules) for 12 weeks. Arm 2 (control group): no caffeine and four cups of water per day for 12

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy adult males and females (aged 18+) 2. Weight stable for 3 months 3. People who do not drink tea and coffee regularly

Exclusion criteria

Exclusion criteria: 1. Those taking any prescription medicines (excluding contraceptives) within the last 3 months 2. Regular smokers 3. Regular tea and coffee drinkers 4. Medical conditions including heart disease, diabetes, gastrointestinal diseases, liver disease and endocrine diseases 5. Those following a weight-reducing diet

Design outcomes

Primary

Measure	Time frame
1. 2-hour liquid meal tolerance test (glucose, insulin and triglycerides) 2. Fasting glucose 3. Insulin 4. Adiponectin 5. Inflammatory markers 6. Lipids Measured at baseline and after 12-week intervention.	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026