Elective caesarean section Pregnancy and Childbirth Caesarean section
Conditions
Interventions
Following informed consent, simple randomisation using a random number table was performed by the investigational pharmacy staff. Infusion bags were prepared in accordance with randomisation and the b
Sponsors
Istanbul Bakirkoy Women and Children Hospital (Turkey)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Subjects older than 38 weeks estimated gestational age 2. Requiring elective caesarean section 3. Females aged 20 - 40 years
Exclusion criteria
Exclusion criteria: Any risk factor associated with an increased risk of postpartum haemorrhage: 1. Anaemia (Hb less than 7 g%) 2. Multiple gestation 3. Antepartum haemorrhage 4. Uterine fibroids 5. Polyhydramnios 6. Emergency caesarean section 7. A history of uterine atony and postpartum bleeding 8. Current or previous history of significant disease including heart disease, liver, renal disorders or known coagulopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantity of blood postpartum, measured from one day before the caesarean section and two days after the caesarean section | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured from one day before the caesarean section and two days after the caesarean section: 1. Excessive bleeding rate 2. Blood transfusion 3. The use of additional uterotonic agents reflecting atony (such as an oxytocin infusion or Prostaglandin F2a) 4. Incidence of tranexamic acid side effects 5. Post-natal length of stay for the mother 6. Neonatal outcomes | — |
Countries
Turkey
Outcome results
None listed