Effects of exercise on physical and metabolic function of candidates before undergoing bariatric surgery

Effects of exercise intensity on physical and metabolic function of candidates before undergoing bariatric surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN42273422

Enrollment

Registered

2023-04-21

Start date

2021-07-01

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment of cardiometabolic dysfunctions in people with obesity Nutritional, Metabolic, Endocrine

Interventions

Randomised control trial, where two different pre-surgical exercise programs will be compared (HIIT versus MICT). Each group will have 15 participants randomly allocated, and both training programs wi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 60 years old 2. Planned to undergo sleeve gastrectomy

Exclusion criteria

Exclusion criteria: 1. Attending supervised exercise sessions 2. Medical contraindications to performing physical activity 3. Declaring functional limitations which disallow them to complete a progressive cardiorespiratory fitness test 4. Uncontrolled neuropsychiatric illnesses

Design outcomes

Primary

Measure	Time frame
Insulin resistance measured using blood glucose, insulinaemia, and HOMA-IR during fasting and after an oral glucose tolerance test at baseline (pre-training), post-training, 1 month after bariatric surgery, and 6 months after bariatric surgery.	—

Secondary

Measure	Time frame
The secondary outcome measures are measured at baseline (pre-training), post-training, 1 month after bariatric surgery, and 6 months after bariatric surgery: 1. Muscle strength measured using a hand dynamometer and isokinetic chair 2. Cardiorespiratory fitness measured using a Modified Bruce protocol 3. Static balance measured using posturography 4. Anthropometric measurements including weight, height, waist and hip circumference, and body composition measured using bioimpedance 5. Spontaneous physical activity measured using the IPAQ questionnaire 6. Metabolic function including circulating levels of thyroid hormones (TSH), transaminases (ALT and AST), lipid profile, hemogram, electrolytes (Na, Cl, P), albumin, bilirubin, creatinine, and urea nitrogen measured using standard laboratory procedures	—

Measure

Time frame

The secondary outcome measures are measured at baseline (pre-training), post-training, 1 month after bariatric surgery, and 6 months after bariatric surgery: 1. Muscle strength measured using a hand dynamometer and isokinetic chair 2. Cardiorespiratory fitness measured using a Modified Bruce protocol 3. Static balance measured using posturography 4. Anthropometric measurements including weight, height, waist and hip circumference, and body composition measured using bioimpedance 5. Spontaneous physical activity measured using the IPAQ questionnaire 6. Metabolic function including circulating levels of thyroid hormones (TSH), transaminases (ALT and AST), lipid profile, hemogram, electrolytes (Na, Cl, P), albumin, bilirubin, creatinine, and urea nitrogen measured using standard laboratory procedures

—

Countries

Chile

Contacts

Public ContactIngrid Pamela Ehrenfeld-Slater

facmed@uach.cl+56 63 2221324

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 8, 2026