Platelet-rich plasma changes after bilateral low-load knee extensions under blood-flow restriction in the athletic population Circulatory System
Conditions
Interventions
Before the intervention, participants will have a pre-exercise peripheral vein catheterization, blood sample draw, and PRP preparation for baseline measurements. Each participant will undergo standard
Sponsors
International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Healthy individuals undergoing routine health screening 2. Aged between 18 and 40 years 3. No musculoskeletal conditions that would interfere with exercise
Exclusion criteria
Exclusion criteria: 1. Systemic inflammatory diseases 2. Cardiovascular risk factors 3. Any blood dyscrasia 4. Tegner Activity scale score <5 5. Under nonsteroidal anti-inflammatory drugs and aspirin treatment within 1 week before testing 6. Previously performed exercises on the testing day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IGF-1 and IL-6 plasmatic concentrations measured by immunoassay analysis at baseline, 10, 20 and 30 minutes after bilateral knee extensions under blood-flow restriction therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Platelet and leukocyte plasmatic concentrations measured with an automated cell counter at baseline, 10, 20 and 30 minutes after bilateral knee extensions under blood-flow restriction therapy | — |
Countries
Venezuela
Contacts
Public ContactTheodorakys Marín Fermín
Outcome results
None listed