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Determining the optimal approach to identifying individuals with chronic obstructive pulmonary disease

Determining the optimal approach to identifying individuals with chronic obstructive pulmonary disease: a multi-centre randomised trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN42132522
Enrollment
600
Registered
2011-03-31
Start date
2011-05-01
Completion date
Unknown
Last updated
2018-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease (COPD) Respiratory Chronic obstructive pulmonary disease (COPD)

Interventions

1. Participants will undertake lung function tests (i.e. peak flow measurement, microspirometry and post-bronchodilator spirometry), a wheeze-detecting device (i.e. wheezometer) and a case-finding que
a screening questionnaire and a follow-up questionnaire. All participants receive the case-finding tests, with half randomised to receive the tests straight away and the remainder wil

Sponsors

University of York (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Current smokers aged 35 years or more who are registered with participating GP practices

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Recent history (within 8 weeks) of myocardial infarction, stroke, pulmonary embolism, chest/abdominal surgery or eye surgery 3. Any mental or physical condition (e.g. chest/abdominal pain/stress incontinence) or any other condition which means the participant is unable to undergo the case-finding tools

Design outcomes

Primary

MeasureTime frame
Effectiveness of diagnostic pathways - aim to identify the most effective pathway for use as the routine service model in primary care

Secondary

MeasureTime frame
1. Cost-effectiveness of COPD case-finding pathway 2. Efficiency of COPD case-finding pathway 3. Impact on smoking behaviour

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026