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A feasibility study of no routine gastric residual volume measurement in mechanically ventilated Infants and children: the GASTRIC Study

A feasibility study of no routine gastric residual volume measurement in mechanically ventilated Infants and children: the GASTRIC Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN42110505
Enrollment
1200
Registered
2018-02-16
Start date
2018-05-01
Completion date
Unknown
Last updated
2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill tube fed neonates and children Not Applicable

Interventions

This feasibility study will examine clinician and parent views around a trial of not undertaking this routine intervention of GRV measurement and once trial inclusion/exclusion criteria are agreed the

Sponsors

University Hospitals Bristol
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Healthcare professionals working in UK PICU and NICUs who are involved in decision-making around feeding (nurses, doctors and dieticians) 2. Parents of children who have been in a UK PICU or NICU

Exclusion criteria

Exclusion criteria: Non PICU or NICU staff or parents who have not had this experience

Design outcomes

Primary

MeasureTime frame
Possibility of conducting a trial of not measuring gastric residual volume (GRV) in UK pediatric and neonatal intensive care units

Secondary

MeasureTime frame
1. Standard care practices around enteral feeding and GRV measurement assessed using an e-survey in all UK PICUs and NICUs 2. Healthcare professionals (nurses, doctors and dietitians) views around GRV measurement, acceptability of not measuring GRV, alternative methods to assess feed tolerance, willingness to randomise to or comply with a future trial, barriers to recruitment, perceived training needs and inclusion and exclusion criteria 3. PICU and NICU parents' and/or patients' views around GRV measurement, acceptability of not measuring GRV, willingness to agree to a future trial, barriers to recruitment, patient (parent) centred outcomes and information needs for parents 4. Consensus on future trial issues including optimal trial design, primary and secondary outcome measures and inclusion and exclusion criteria 5. Trial feasibility (in both PICU and NICU) assessed using routinely collected national clinical datasets (PICANet and NNRD) and sample size calculations for a future trial 6. A standard (control) arm (with routine GRV measurement) and an intervention arm (no routine GRV measurement) of a future trial, agreed using a consensus process The questionnaires are currently being developed as no existing tools are suitable. There will be one baseline measurement (at 1 month) of existing practice, then a further questionnaire around optimal research design at month 4.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026